The answer you refer to is incorrect. He does not understand molecular genetics.
1. A gene is information. The information is stored as a series of nitrogenous bases. Information can change. That is called mutation. The analogy is that the DNA letters are put in an order that spells out words, sentences, paragraphs. Change a letter and It changes the meaning. It leads to a different meaning but there is the information is still there. It can mean something else. Likewise, a change in DNA can lead to a different product. However, it's still information. The sickle cell anemia mutation is a single change in a base that leads to a protein with a change in one amino acid. It is useful if one is living in an area where malaria is endemic. This is a change that gives a benefit to an individual with a single sickle cell allele. How is that losing information?
And single letter changes are not the only type of mutation. There are duplications of entire genes or genomes, as if you copied an entire paragraph. One copy is still there to function as normal, but the other copy is free to change. That is seen in the hemoglobin lineage.
How is going from one globin gene to dozens (there are multiple copies of the various globins) losing information?
Finally, Hugo de Vries lived in the 19th century. I think we've learned just a wee bit more in that time. We do know how the fittest arrive. Why not go back further in time and get someone who thought that people get sick because of ill humors or possession by demons?
Werner Gitt is a creationist who is extrapolating from his work in computer science into living systems. The argument he uses is that all information in a computer has to come from an intelligent being. A computer does not create its own program or design. Then he extends the analogy to living systems. He claims that because living things are complicated, an even more complicated thing must have created them. The problem is that his analogy is not valid. Computers are inanimate machines and living things are exactly that. Living. Organisms are capable of replicating, carrying all the information needed for life stored in DNA and subject to Natural Selection. Just because mutations are random does not mean that evolution is random. Natural Selection is anything but random. It SELECTS.
=====================
Addendum:
Since questioner is refuses to accept anything that contradicts what he wants to believe and continues to put forth the same, illogical responses, I'll just cut and paste myself.
Dr Spetner is a physicist (can’t find a credible biologist to use?) who is well outside his area of expertise, which is clear if he really did say, “all point mutations…reduce genetic information.” He left APL at Johns Hopkins in 1970. It is safe to say that quite a lot has happened in biology since then.
There are numerous cases where a single nucleotide change gives rise to new or modified function.
A single amino acid change increases the esterase activity of Lc(alpha)E7 making insects resistant to pesticides.
A single amino acid change converts a violet photopigment (SWS1 opsin) into an ultraviolet photopigment in insects letting them see in the ultraviolet range.
A single amino acid change in a sodium channel makes flies resistant to DTT.
A single amino acid in cry2 alters flowering time in plants.
A single amino acid change in Hemoglobin b gives frogs enhanced oxygen transport at high altitude.
In each case, a single mutation is sufficient to give the organism an adaptive trait.
=============================
As for mutations that confer increase binding (specificity) there is a recent report out on the evolution of steroid receptors that shows how mutations in a two key amino acids makes a mineralocorticoid receptor into a receptor that has higher affinity for glucocorticoid. Gene duplication and divergence yields two receptors, each specific of its ligand. Again, an obvious increase in information and specialization.
Another mutation that leads to increased binding is fetal hemoglobin gamma where a single amino acid difference between it and hemoglobin alpha gives it higher affinity for oxygen than adult hemoglobin. Again, an obvious gain of information where multiple versions of related genes allowed the development of placental mammals.
Someone else has already taken apart the arguments of Spetner so there is no need for me to comment further here.
http://www.talkorigins.org/faqs/information/spetner.html
As for Behe, his arguments against Natural Selection have been effectively destroyed and refuted by many others so no need to comment further. At the risk of judging a book by it's title, it seems that he has not learned anything and continues his argument of ignorance. Instead of proposing a better model, he only points out (or attempts to) the limitations of the accepted theory of evolution by natural selection. The basis of his arguments being a religious one and not one reasoned through evidence and scientific methodology as he was forced to admit in the recent Dover, Delaware court case.