Question:
Biology Gentics Blood types MN, Rh, ABO PRoblem Help...? PLS?
eri
2007-05-31 11:57:11 UTC
Find the probability (%) of each father?

We have a mother with blood type A, M, Rh+
and her child O, MN, Rh-
The father prob.
1. A, N, Rh +
2. O, MN , Rh-
________________
I don't understand the system with MN;
I made some combination only with blood types in ABO system and Rh. So, I found:
for the first father the percentage is 6.25%
and for the second 25%

please help
Five answers:
Mark S, JPAA
2007-05-31 12:43:56 UTC
A couple of things first: the MN locus is co-dominant, meaning that both can be expressed (first link).



The ABO blood group is the same way, except that O means the absence of either A or B (second link).



The Rh group is a single locus, and the Rh- allele is recessive (third link)



So, knowing all this, the mother has to be (AA or AO)/MM/(Rh+Rh- or Rh+Rh+) to get her own phenotype. However, we already know that the child is O, so the mother can't be AA and thus has to be AO; that is, AO/MM/(Rh+Rh- or Rh+Rh+). Again, since the child is Rh- the mother would have to be Rh+Rh-, so she is:



AO/MM/Rh+Rh-



If the child is O, MN, Rh- then given the dominance patterns we know that any father has to be (AO or OO)/(MN or NN)/(Rh+Rh- or Rh-Rh-). So the first father is AO/NN/Rh+Rh- and the second one is OO/MN/Rh-Rh-



So, doing Punnett squares, the first father is 25% likely to give an O (OO) child, while the second father is 50% likely.



Similarly, the N (NN) father is 100% likely to give an MN child; the MN father is 50% likely.



Finally, the Rh+Rh- father will give any Rh- children 25% of the time and the second father will have odds of 50%.



So, overall:



1st father = 25% * 100% * 25% = 12.5%



2nd father = 50% * 50% * 50% = 12.5%



Check my math and genotypes, but I think I did this right.
2015-08-17 01:38:35 UTC
This Site Might Help You.



RE:

Biology Gentics Blood types MN, Rh, ABO PRoblem Help...? PLS?

Find the probability (%) of each father?



We have a mother with blood type A, M, Rh+

and her child O, MN, Rh-

The father prob.

1. A, N, Rh +

2. O, MN , Rh-

________________

I don't understand the system with MN;

I made some combination only with blood types in ABO system and Rh. So, I...
giftedman88
2007-05-31 12:30:39 UTC
And is it homozygous or heterozygous A for the mother?????

If it's homozygous A then the father would be:

100% A(heterozygous), 0% O, 0% Rh+, 100% Rh-



If it's heterozygous A then

50% A, 50% O, 0% Rh+, 100% Rh-



Okay i see

So it's always Homozygous right.....

0% N, 50% M, 50% MN
hiott
2016-10-31 04:31:35 UTC
Blood Type Punnett Square Problems
2007-05-31 12:12:12 UTC
Can you plz post this question on http://www.tutorbuddy.org ? I will answer as soon as you post


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