Prokaryotic/Eukaryotic DNA Replication?

Question

Question asks:
Unlike prokaryotic DNA replication, eukaryotic DNA replication __________.
(A) is completed by DNA polymerase
(B) cannot be completed by DNA polymerase
(C) is semiconservative
(D) has a single origin
(E) is error free

I know that both of them are completed by DNA polymerase and that only prokaryotes have a single origin. I chose C but I'm not sure if D is incorrect. (Unfortunately, the answer given is "0"...which doesn't make any sense!)

Answer 1

The answer is B, although it isn't entirely correct. Eukaryotic DNA replication runs into a problem at the end of the chromsome (at the telomere) as stated by bio. There is a special enzyme complex called telomerase which is composed of a couple of subunits and an RNA primer molecule, which technically makes telomerase an RNA-dependent DNA polymerase (a reverse transcriptase) that replicates the telomere region. So, a different type of DNA polymerase (telomerase) actually completes the replication at the ends of the chromosomes. So, saying that DNA polymerase cannot complete eukaryotic DNA replication is somewhat correct if you consider telomerase to not be the standard DNA polymerase (even though it is a type of DNA polymerase, an RNA-dependent DNA polymerase).

Answer 2

B.



It can't be completed by DNA polymerase because of the telomeres (the edges of the chromosomes).

The telomeres can not be replicated by DNA polymerase because no DNA primer can be used at the edge of the chromosome.

In Prokaryotic chromosome there is no such problem because they are circular and has no edge.

Answer 3

B) cannot be completed by DNA polymerase

Eukaryotic cells have linear DNA so they require Telomerase for replication of the telomeric ends.

While no such problem arises in case of prokaryotic cells as they have circular DNA

Answer 4

B- cannot be completed by DNA polymerase, in eukaryotic DNA replication Ligase completes the lagging strand by joining the okazaki fragments.

Answer 5

A boiled egg and an omelette - the boiled egg representing the eukaryotic cell (yolk being the membrane bound nucleus) and an omelette representing the prokaryotic cell!

Answer 6

d i scorrect.